Epigenetics and Nanomedicine
The Epigenetics and Nanomedicine research group was established in 2015 as a result of the CINN’s growing activity in the biomedical field.
The current research lines are focused on eight main areas:
- Application of new technologies in the search for epigenetic biomarkers related to aging and human carcinogenesis that are useful in clinical practice
- Development of nanoparticles for the administration of combination of antitumor epigenetic drugs
- Identification of epigenetic changes in response to nanomaterials, particularly graphene and graphenic materials
- In-situ analysis of subcellular architecture
- New inorganic antimicrobial products
- Omics in health: Advanced techniques to study the bioactive role of food
- Tissue engineering: Solutions against peri-implantitis, ceramic materials for long-lasting implants, bone substitutes
- Identification and pharmacological manipulation of the molecular mechanisms involved in the signaling of Bone Morphogenetic Proteins (BMPs)
- Computational biochemistry of membrane receptors
- Study of sarcomas and the evolution of tumor subpopulations during tumor progression and in response to anticancer treatments
Our researchers lead 6 research groups of the Health Research Institute of the Principality of Asturias (ISPA):
- Subcellular architecture. Dr. José Jesús Fernández
- Cancer Epigenetics and Nanomedicine. Prof. Mario Fernández Fraga
- Nanomaterials and Tissue Engineering. Dr. Adolfo Fernández Valdes
- Proteomics Unit. Dr. Ignacio Ortea
- Tissues-specific BMPs signalling. Dr. Gonzalo Sánchez Duffhues
- Sarcomas and Experimental Therapies.Dr. René Rodríguez González
