Projects
Identification of alterations in the subcellular architecture of peripheral tissues in Huntington’s disease
Huntington’s disease (HD) is an inherited disease that involves selective neurodegeneration of medium-sized spiny neurons of the striatum and subsequently of neurons of the cerebral cortex. One of the major limitations that exist in the study of HD progression is that studies of brain deterioration are limited to the use of non-invasive imaging techniques and […]
Eradication of indirect contact transmission of SARS-CoV-2 by developing antimicrobial surfaces with inorganic antimicrobial additives
The project aims to develop, as a preventive measure to limit the spread of the SARS-CoV-2 virus, antimicrobial surfaces capable of eliminating or significantly reducing the viral load on them.
Design of molecular targets for rapid and efficient identification of SARS-CoV-2 RNA species in CoVid-19 patients
Abstract Due to the health emergency caused by the outbreak of the CoVid-19 pandemic, an immediate response is urgent for the development of tools that facilitate the detection and monitoring of patients susceptible to infection with the SARS-CoV-2 virus. This project aims to generate an alternative, fast and simple test for the direct detection of […]
Impact of dietary intervention on tumoral inmunity-DIgesT
Disease progression can be controlled in cancer patients through the administration of immune checkpoint inhibitors (ICIs). But, ICIs mainly show efficacy in subsets of patients and treatment costs are very high. Here, we use a dietary intervention to counteract cancer-related immune suppression through interfering with metabolic pathways. DIgesT will enable the exciting possibility of integrating cancer therapy with […]
ECOPLACKAGING-Vegetal fibres-reinforced PLA antimicrobial composites for packaging applications
Scope Ecoplackaging aims to develop a fully biodegradable bioplastic composite consisting of a PLA matrix reinforced with: 1) vegetal fibres obtained from plant waste, namely island invasive plant species and 2) low-cost and environmentally-friendly antimicrobial glasses. The main project objectives are: To achieve sustainable bioplastic materials with suitable mechanical and antimicrobial properties thanks to the […]
Identification of therapeutic targets in colon cancer through epigenetic edition
In recent years, the analysis of genome-wide DNA methylation patterns has made it possible to identify new biomarkers in colorectal cancer (CRC). Even though many of these alterations can be useful in the diagnosis, prognosis or even evaluation of response to treatment, their value as possible therapeutic targets has proven to be much more limited, […]
New reactivity ways of coordinated N-heterocycles to metal fragments
Abstract The generation, storage and consumption of energy from a more sustainable approach, and the need of more efficient and less aggressive therapeutic agents, require basic science to carry out the development of new functional molecules with a variety of applications, such as photoprotective materials, catalysts for the transformation of CO2 into fuels and useful […]
Carbon ultramaterials for thermal management (Ultrathermal)
Scope The main objective of this project is to optimize and complete the design, synthesis, processing and characterization of a new generation of bulk carbon-ceramic composite materials with ultrahigh thermal conductivities, close to those of diamond or graphene. Project Details Call: National Programme for Research Aimed at the Challenges of SocietyProject code: RTI2018-102269-B-100Duration: 01/01/2019-31/12/2021Funding: 121.000 […]